Respiratory

Oxygenation Index (OI)

Assesses the severity of hypoxic respiratory failure.

Parameters

%
cmH₂O
mmHg

Oxygenation Index (OI) Result

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FormulaOI = (FiO₂ [%] × Mean Airway Pressure [cmH₂O]) / PaO₂ [mmHg]

Clinical Pearls

OI is the preferred marker of illness severity in pediatric ARDS and persistent pulmonary hypertension of the newborn (PPHN). An OI > 40 is a classic threshold for considering extracorporeal membrane oxygenation (ECMO).