Respiratory
Oxygenation Index (OI)
Assesses the severity of hypoxic respiratory failure.
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Parameters
Oxygenation Index (OI) Result
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Formula
OI = (FiO₂ [%] × Mean Airway Pressure [cmH₂O]) / PaO₂ [mmHg]Clinical Pearls
OI is the preferred marker of illness severity in pediatric ARDS and persistent pulmonary hypertension of the newborn (PPHN). An OI > 40 is a classic threshold for considering extracorporeal membrane oxygenation (ECMO).