Nephrology
CRRT Effluent Dose & KDIGO Target Calculator (CVVH / CVVHD / CVVHDF)
Calculates continuous renal replacement therapy effluent dose (mL/kg/hr) and pre-dilution correction.
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Parameters
CRRT Effluent Dose & KDIGO Target Calculator (CVVH / CVVHD / CVVHDF) Result
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Formula
Prescribed Effluent (mL/kg/hr) = (Qdialysate + Qreplacement + Qultrafiltration) / Weight (kg)
Delivered Dose corrects convective clearance by Pre-dilution Factor: Qb(1-Hct)*60 / (Qb(1-Hct)*60 + Qrep,pre)Clinical Pearls
Prevents underdosing and wasteful overdosing of continuous dialysis while avoiding dangerous drug clearance fluctuations in septic shock and AKI.
Limitations
Calculations should use dry baseline weight rather than fluid-overloaded weight.